Skip to content

Head to head

Mela B3 Dark Spot Serum with Melasyl + Niacinamide vs PDRN Pink Peptide Serum

La Roche-Posay Mela B3 Dark Spot Serum with Melasyl + Niacinamide edges out Medicube PDRN Pink Peptide Serum, 7.6 to 7.3. It wins on results, formula and community love, while the PDRN Pink Peptide Serum is stronger on texture and feel and value.

Benefit fingerprints

What each one does.

La Roche-Posay Mela B3 Dark Spot Serum with Melasyl + Niacinamide

HydrateClarifyRenewGlowCalm & ProtectHair & ScalpFinish & WearScentMoistureBarrierBreakoutsOil & PoresCleanseLines & FirmnessTextureEye AreaEven ToneRadianceSensitiveProtectRepairShape & ShineScalpFinishWearCoverageLashes & BrowsFloralGourmandFreshWoody & AmberHydratingPlumpingLong-lasting moistureBarrier repairDryness reliefFlaking reliefAcneBlackheadsClogged poresOil controlPore refiningShine controlMakeup removalDouble cleansingFine linesFirmingCrepinessSmoothingResurfacingBumps & KPDark circlesPuffinessDark spotsHyperpigmentationAcne marksBrighteningDullnessGlass skinSoothingRednessIrritation-freeUV protectionNo white castAntioxidantOdor controlDamage repairSplit endsHeat protectionCurl definitionFrizz controlVolumeShineScalp careHair growth supportDandruffColor protectionMatteDewySatinNaturalLong-wearTransfer-proofWaterproofBuildableSheer coverageMedium coverageFull coverageBlurringLash lengthLash volumeCurl holdBrow definitionFloralWhite floralRoseVanillaGourmandCaramelCitrusFresh & cleanAquaticGreenWoodyAmberMuskySpicyHydrateClarifyRenewGlowHair & ScalpFinish & WearScent

Medicube PDRN Pink Peptide Serum

HydrateClarifyRenewGlowCalm & ProtectHair & ScalpFinish & WearScentMoistureBarrierBreakoutsOil & PoresCleanseLines & FirmnessTextureEye AreaEven ToneRadianceSensitiveProtectRepairShape & ShineScalpFinishWearCoverageLashes & BrowsFloralGourmandFreshWoody & AmberHydratingPlumpingLong-lasting moistureBarrier repairDryness reliefFlaking reliefAcneBlackheadsClogged poresOil controlPore refiningShine controlMakeup removalDouble cleansingFine linesFirmingCrepinessSmoothingResurfacingBumps & KPDark circlesPuffinessDark spotsHyperpigmentationAcne marksBrighteningDullnessGlass skinSoothingRednessIrritation-freeUV protectionNo white castAntioxidantOdor controlDamage repairSplit endsHeat protectionCurl definitionFrizz controlVolumeShineScalp careHair growth supportDandruffColor protectionMatteDewySatinNaturalLong-wearTransfer-proofWaterproofBuildableSheer coverageMedium coverageFull coverageBlurringLash lengthLash volumeCurl holdBrow definitionFloralWhite floralRoseVanillaGourmandCaramelCitrusFresh & cleanAquaticGreenWoodyAmberMuskySpicyHydrateClarifyRenewGlowHair & ScalpFinish & WearScent

Side by side

Every detail, compared.

We may earn a commission when you buy through links on this page. It never affects our scores or what we recommend. How we make money

Beauty score
7.6Good
7.3Good
Results30% of score
7.6
7.0
Formula & ingredients20% of score
8.0
7.2
Texture & experience15% of score
7.6
7.8
Value20% of score
7.2
7.6
Community love15% of score
7.4
7.2
Community
No ratings yet
No ratings yet
PriceTypical, checked by our editors
$44.99/ 1 fl oz / 30 mlMid-range
$26.00/ 1.01 fl oz / 30 mlMid-range
Price per ounceLowest wins
$44.35 / oz
$25.63 / oz
What it does
  • Dark spots
  • Hyperpigmentation
  • Acne marks
  • Brightening
  • Brightening
  • Firming
  • Fine lines
  • Hydrating
Made for
All skin types, Normal skin, Combination skin, Oily skin
All skin types, Dry skin, Sensitive skin
Format
Serum
Serum
Texture
Lightweight serum, per La Roche-Posay
Lightweight, super-moisturizing pink serum that Medicube says absorbs within minutes; the color comes from vitamin B12 and does not stain
Fragrance-free
No — contains fragrance
No — contains fragrance
Claims
Non-comedogenic, Dermatologist-tested, Paraben-free
Dermatologist-tested
Brand origin
🇫🇷 French pharmacy
🇰🇷 K-beauty
Video reviews
Best for
  • • Persistent dark spots and post-acne marks
  • • Hydroquinone-free routines for deeper skin tones
  • • People already using daily sunscreen
  • • Trying PDRN in a lightweight daily serum
  • • Dull or dehydrated skin that wants a glow-focused step
  • • Shoppers who want a vegan option, via the rose-PDRN variant
Strengths
  • Melasyl, a new multi-patented anti-discoloration ingredient, plus 10% niacinamide
  • Brand study: 90% saw improvement in persistent dark spots after 8 weeks
  • Tested on sensitive skin, allergy tested and non-comedogenic
  • Combines PDRN, niacinamide and five peptides in one lightweight serum
  • Light, fast-absorbing texture suited to morning and night use
  • Sold in a salmon-DNA version and a vegan rose-PDRN version
Watch-outs
  • Contains fragrance and several silicones
  • Results reported by creators are gradual and inconsistent
  • Contains added fragrance despite a 'formulated without fragrances' claim on the page
  • Peptides appear near the end of the ingredient list
Where to buy

Affiliate links — we may earn a commission. How we make money

FAQ

Quick answers.

Which is better, Mela B3 Dark Spot Serum with Melasyl + Niacinamide or PDRN Pink Peptide Serum?

La Roche-Posay Mela B3 Dark Spot Serum with Melasyl + Niacinamide edges out Medicube PDRN Pink Peptide Serum, 7.6 to 7.3. It wins on results, formula and community love, while the PDRN Pink Peptide Serum is stronger on texture and feel and value.

Which is better value?

La Roche-Posay Mela B3 Dark Spot Serum with Melasyl + Niacinamide works out to about $44.35 / oz and Medicube PDRN Pink Peptide Serum to about $25.63 / oz, based on typical non-Amazon retail prices when we last checked.

How do you score them?

Both are scored on the same five-factor rubric (results, formula & ingredients, texture & experience, value, community love), using the formula or specs, verified creator reviews, community consensus and value. Brands can’t pay for placement.