
La Roche-Posay
Mela B3 Dark Spot Serum with Melasyl + Niacinamide
A dark-spot serum pairing La Roche-Posay's new Melasyl molecule with 10% niacinamide; promising brand data, mixed real-world results.
A $12 tranexamic-derivative and niacinamide serum with full ingredient percentages, a budget favorite for marks and uneven tone.
Beauty score
#2 of 9 serums
Community
—/10
Made for: All skin types · Oily skin · Combination skin · Acne-prone skin
Last reviewed November 2, 2026 by our editors · How we score
The verdict
A $12 tranexamic-derivative and niacinamide serum with full ingredient percentages, a budget favorite for marks and uneven tone.
Good Molecules Discoloration Correcting Serum pairs cetyl tranexamate mesylate, a tranexamic acid derivative, with 4% niacinamide in a lightweight, fragrance-free serum. The brand discloses every ingredient percentage, and the formula targets dark spots, post-acne marks and uneven tone. Creators have published trials of one week to two months, and it is a popular low-cost entry into tranexamic acid. Results are gradual and depend on consistent use with sunscreen, and the brand's pages list the derivative at both 2% and 3%.
Best for
What we love
Worth knowing
How it scored
Five factors, weighted for formulas. Here’s our working.
Beauty score out of 10. Brands can’t pay for placement — ever.
One creator credits it with lighter dark marks and clearer skin, and two-month creator trials show before-and-after comparisons, but fading is gradual.
Tranexamic acid derivative plus 4% niacinamide in a minimal, fragrance-free base with every percentage disclosed; the derivative is less studied than tranexamic acid itself.
A lightweight, fragrance-free serum that layers under moisturizer and is meant for twice-daily use.
$12 for 30 mL, with a 75 mL size for $25, is among the cheapest tranexamic acid options.
Widely covered by budget-skincare creators and doctor-led channels as an affordable hyperpigmentation serum.
Beauty profile
Texture
Lightweight serum, per Good Molecules
Format
Fragrance
Size
Key ingredients
Ingredient encyclopedia →What’s in it: 4% niacinamide and cetyl tranexamate mesylate (a tranexamic acid derivative), listed at 3% in the version 2.0 ingredient table and 2% in the page copy; pH 5.5.
How to use
Apply a few drops in the morning and at night before oils and moisturizers; suitable for daily use. Discontinue use if irritation occurs.
Free from (brand-stated)
Claims & certifications
Formulas change. Always check the packaging, and patch-test if your skin is reactive.
Creator video reviews
Real reviews, try-ons and wear tests from independent creators — verified with TikTok and YouTube and labelled when sponsored.
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What people say
Verbatim from Reddit, forums, blogs and the beauty press — linked, so you can read the whole thread.
1 verbatim quote · 1 positive
What I did to fade my acne dark spots is by using Good Molecules' Discoloration Correcting Serum paired with their 10% niacinimide. The formulas are strong but didn't irritate my skin and I pretty much saw a big difference.
Price & value
Typical price
$12.00
for 1 fl oz / 30 ml
Per ounce
$11.83
About 47% less per ounce than the typical serums we review. Our value score: 9.4/10 for a drugstore pick.
Price checked November 2026 at a non-Amazon retailer. Prices change — retailers show the current one.
Where to buy
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FAQ
It contains cetyl tranexamate mesylate, which Good Molecules describes as an advanced form of tranexamic acid, alongside 4% niacinamide.
Yes. Good Molecules says to apply a few drops morning and night before oils and moisturizers and that it is suitable for daily use.
The brand says it never tests on animals, and the formula is labeled vegan and fragrance-free with no PEGs, mineral oils, alcohols or ethoxylated ingredients.
Alternatives

La Roche-Posay
A dark-spot serum pairing La Roche-Posay's new Melasyl molecule with 10% niacinamide; promising brand data, mixed real-world results.

The Ordinary
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Beauty of Joseon
A cushiony propolis-and-niacinamide serum with a low price and a devoted following for glow, calm and smoother-looking pores.

Differin
The formerly prescription-only 0.1% adapalene gel, now OTC: a proven, inexpensive acne retinoid that demands patience through dryness.