
The Ordinary
Multi-Peptide Serum for Hair Density
An affordable leave-on peptide and caffeine scalp serum for fuller-looking hair; reviewers see modest results with consistent nightly use.
Hair & scalp· in 4 products
Also listed as Caffeine (INCI) and 1,3,7-trimethylxanthine
Caffeine appears in scalp tonics and shampoos marketed for thinning hair, and in eye creams marketed for puffiness. It penetrates skin readily, including through hair follicles.
What it does
In lab studies caffeine counteracted testosterone's inhibitory effect on hair follicles and prolonged the growth phase. A 2017 open-label randomized study found a 0.2% caffeine liquid was not inferior to 5% minoxidil for men with androgenetic alopecia over six months, though it was industry-sponsored and lacked a placebo. In eye products, caffeine's vasoconstrictive effect may temporarily reduce the look of puffiness.
Emerging evidence
Lab and penetration data are solid, but clinical trials for hair are few, mostly sponsored and lack placebo controls.
In our directory: It’s a key ingredient in 4 products we review, most often eye & lip and moisturizers. Those products are mostly built for hydrating, long-lasting moisture and brightening. In formulas, it most often shares the label with green tea, hyaluronic acid and glycerin.
Reach for it for
Usually a good fit for
How to use it
Massage a leave-on caffeine scalp liquid into dry or towel-dried scalp daily, or leave caffeine shampoo on for about two minutes. Pat eye cream gently around the orbital bone.
Layering
Pairs well with
Before you start
Topical caffeine is well tolerated. Shampoo contact time is short, so leave-on products deliver more. Persistent or sudden hair loss warrants a dermatologist visit, since proven treatments such as minoxidil exist.
References
Educational, not medical advice. Ingredient guides summarise published research and expert guidance; formulas and concentrations differ between products.
4 products
4 products

The Ordinary
An affordable leave-on peptide and caffeine scalp serum for fuller-looking hair; reviewers see modest results with consistent nightly use.

The Ordinary
A budget caffeine and green-tea eye serum that visibly de-puffs for many users, but feels tacky and needs an eye cream on top.

Clinique
A refreshing, oil-free aloe and hyaluronic acid gel-cream that excels at light, fast hydration rather than heavy barrier repair.

Kiehl's
Kiehl's rich avocado oil eye cream (formerly Creamy Eye Treatment) hydrates dry under-eyes well, but it is pricey and heavy for some.
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