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Hydrators· in 12 products

Panthenol

Also listed as Dexpanthenol, D-panthenol, Provitamin B5 and Panthenol (INCI)

Moderate evidence 1–5% in leave-on skin care

Panthenol is the alcohol form of pantothenic acid (vitamin B5) that skin converts to the vitamin. It is a humectant and skin-conditioning ingredient used in moisturizers, barrier creams, lip balms and hair conditioners.

12PaPanthenolHydrators

What it does

The short version.

Panthenol draws water into the outer skin layer and helps reduce water loss, so it leaves skin feeling softer and less tight. Studies of dexpanthenol creams, mostly from the 1990s and 2000s and often sponsored by manufacturers, report improved hydration, smoother skin and less redness after irritation, and support for the skin's natural renewal after minor damage. In hair products it is a film-forming humectant that adds moisture, slip and shine to the hair shaft; it does not change how hair grows.

Moderate evidence

Several small controlled studies and reviews support hydration and soothing effects of topical dexpanthenol, but many are older and industry-funded. Benefits for hair are largely cosmetic (feel and shine).

In our directory: It’s a key ingredient in 12 products we review, most often wash day and serums. Those products are mostly built for hydrating, frizz control and dryness relief. In formulas, it most often shares the label with glycerin, hyaluronic acid and vitamin e.

How to use it

Getting it right.

Use in a serum, moisturizer or balm once or twice daily; it layers easily with most actives. In hair care it is typically found in conditioners and leave-ins.

Layering

Friends & frenemies.

Before you start

Generally well tolerated. Allergic contact dermatitis and contact urticaria to panthenol have been reported but are uncommon; stop use if itching or rash develops.

References

  1. 1Topical use of dexpanthenol in skin disorders — American Journal of Clinical Dermatology (2002), via PubMed
  2. 2Topical use of dexpanthenol: a 70th anniversary article — Journal of Dermatological Treatment (2017), via PubMed

Educational, not medical advice. Ingredient guides summarise published research and expert guidance; formulas and concentrations differ between products.

12 products

Every product with panthenol.

12 products

La Roche-Posay Toleriane Hydrating Gentle Facial Cleanser
Community favorite

La Roche-Posay

Toleriane Hydrating Gentle Facial Cleanser

8.4Great

A fragrance-free, sulfate-free cream cleanser with ceramide-3 and niacinamide that dermatologists keep recommending for dry, sensitive skin.

Cleanser4$19.99
Aquaphor Lip Repair
Best overall

Aquaphor

Lip Repair

8.3Great

A cheap, fragrance-free drugstore lip ointment that reliably soothes chapped, cracked lips without prestige-brand pricing.

Lip balm4
Timeless Skin Care 20% Vitamin C + E Ferulic Acid Serum
Best value

Timeless Skin Care

20% Vitamin C + E Ferulic Acid Serum

8.1Great

The best-known budget take on the C + E + ferulic formula: 20% L-ascorbic acid for $27.95, if you can keep it from oxidizing.

Serum5$27.95
The Ordinary AHA 30% + BHA 2% Peeling Solution
Best value Trending

The Ordinary

AHA 30% + BHA 2% Peeling Solution

8.1Great

The viral red 10-minute at-home peel: strong, cheap and effective on texture, but only for experienced, non-sensitive skin.

Peel5$9.50
COSRX Advanced Snail 96 Mucin Power Essence
Cult favorite Trending

COSRX

Advanced Snail 96 Mucin Power Essence

7.9Good

The K-beauty hydration staple: 96% snail mucin in a lightweight, fragrance-free essence that most skin types tolerate, at a fair price.

Essence5$25.00
Cetaphil Gentle Skin Cleanser
Budget pick

Cetaphil

Gentle Skin Cleanser

7.8Good

The classic milky, fragrance-free cleanser, now sulfate-free with niacinamide and panthenol — basic, gentle and easy to find anywhere.

Cleanser4$12.99
Redken Acidic Bonding Concentrate Shampoo
Community favorite

Redken

Acidic Bonding Concentrate Shampoo

7.7Good

A sulfate-free, low-pH repair shampoo that colorists rate for softness on damaged hair, best used with the rest of the line.

Shampoo5$37.00
SkinCeuticals C E Ferulic with 15% L-Ascorbic Acid
Community favorite

SkinCeuticals

C E Ferulic with 15% L-Ascorbic Acid

7.7Good

The benchmark 15% vitamin C + E + ferulic serum, backed by strong data and derm loyalty, at a price many find hard to justify.

Serum5$185
SheaMoisture Coconut & Hibiscus Curl & Shine Shampoo
Best value

SheaMoisture

Coconut & Hibiscus Curl & Shine Shampoo

7.6Good

An inexpensive sulfate-free shampoo for waves and curls with shea butter and coconut oil, though results vary with hair type.

Shampoo5$12.49
OUAI Wave Spray

OUAI

Wave Spray

7.2Good

A salt-free texture spray for soft, undone beach waves without crunch; easy to use, but pricey for a light-hold mist.

Texture spray5$30.00

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